COVID-19 pandemic

APPRISE is supporting the international research effort to address the novel coronavirus disease (COVID-19) pandemic caused by the SARS-CoV-2 virus.

APPRISE updates:

We recognise the enormous amount of emerging material and aim to provide a reliable source of research links.

[Last updated 27 March 2020]

Global COVID-19 dashboards

Global dashboard of coronavirus COVID-19 cases – from Johns Hopkins CSSE

Novel Coronavirus (COVID-19) situation dashboard – from the World Health Organization

Editorials and comment

  • Cluver et al, Parenting in a time of COVID-19, The Lancet, published online 25 March 2020. Access here.
  • Ritchie and Singanayagam, Immunosuppression for hyperinflammation in COVID-19: a double-edged sword? The Lancet, published online 24 March 2020. Access here.
  • Meyer and Martin, How to reduce COVID-19 spread in long-term care facilities: Challenges and recommendations, Clinicians’ Biosecurity News, published online 23 March 2020. Access here.
  • Chen et al, Detection of Covid-19 in children in early January 2020 in Wuhan, China, NEJM, published online 12 March 2020. Access here.
  • Sharfstein et al, Diagnostic testing for the novel coronavirus, JAMA, published online 9 March 2020. Access here.
  • Fauci et al, Covid-19 — Navigating the uncharted, NEJM, published online 28 February 2020. Access here.
  • Bill Gates, Responding to Covid-19 — A once-in-a-century pandemic? NEJM, published online 28 February 2020. Access here.
  • The novel coronavirus outbreak: What we know and what we don’t, Cell, published online 19 February 2020. Access here.
  • Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China, NEJM, published online 18 February 2020. Access here.
  • Li and de Clercq, Therapeutic options for the 2019 novel coronavirus (2019-nCoV), Nature Reviews Drug Discovery, published online 10 February 2020. Access here
  • Calling all coronavirus researchers: keep sharing, stay open, Nature, published online 4 Feb 2020. Access here
  • Phelan et al, The Novel Coronavirus Originating in Wuhan, China – Challenges for Global Health Governance, JAMA, published online Jan 30, 2020. Access here
  • Emerging understandings of 2019-nCoV, The Lancet, published online Jan 24, 2020. Access here
  • Wang et al, A novel coronavirus outbreak of global health concern, The Lancet, published online Jan 24, 2020. Access here
  • Heymann, Data sharing and outbreaks: best practice exemplified, The Lancet, published online Jan 24, 2020. Access here
  • Munster et al, A novel coronavirus emerging in China – Key questions for impact assessment, NEJM, published online Jan 24, 2020. Access here

Planning and technical guidance

  • World Health Organization, 2019 Novel Coronavirus (2019‑nCoV): Strategic preparedness and response plan, draft as of 3 February 2020. Download PDF
  • World Health Organization, Novel Coronavirus (2019-nCoV) technical guidance, online. Link here

Protocols

  • World Health Organization, Household transmission investigation protocol for 2019-novel coronavirus (2019-nCoV) infection, Version: 1.1, 25 January 2020. Access here
  • World Health Organization, Protocol for assessment of potential risk factors for 2019-novel coronavirus (2019-nCoV) infection among health care workers in a health care setting, version 1.2, 3 February 2020. Access here
  • World Health Organization, The First Few X (FFX) Cases and contact investigation protocol for 2019-novel coronavirus (2019-nCoV) infection, version 2, 10 February 2020. Access here

Research papers (most recent first)

Basic epidemiological and clinical characterisation

  • Zeng et al, Neonatal early-onset Infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China, JAMA Pediatrics, published online 26 March 2020. Access here.
  • Thevarajan et al, Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19, Nature Medicine, published on 16 March 2020. Access here.
  • Li et al, Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2), Science, published on 16 March 2020. Access here.
  • Tang et al, Detection of novel coronavirus by RT-PCR in stool specimen from asymptomatic child, China, Emerging Infectious Diseases, published online 9 March 2020. Access here.
  • Zheng et al, COVID-19 and the cardiovascular system, Nature Reviews Cardiology, published online 5 March 2020. Access here.
  • Guan et al, Clinical characteristics of coronavirus disease 2019 in China, NEJM, published online 28 February 2020. Access here.
  • Lee et al, COVID-19 pneumonia: what has CT taught us?, The Lancet Infectious Diseases, published online 24 February 2020. Access here.
  • Yang et al, Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study, The Lancet Respiratory Medicine, published online 24 February 2020. Access here.
  • Wu and McGoogan, Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China –
    Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA, published online 24 February 2020. Access here.
  • China CDC, Vital surveillances: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) — China, 2020, China CDC Weekly, published online February 17 2020. Access here.
  • Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China, JAMA, published online February 7, 2020. Access here.
  • Chen et al, Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study, The Lancet, published online Jan 29 2020. Access here
  • Backer et al, The incubation period of 2019-nCoV infections among travellers from Wuhan, China, medRxiv, posted Jan 28 2020. Access here
  • Huang et al, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, The Lancet, published online Jan 24, 2020. Access here
  • Zhu et al, A novel coronavirus from patients with pneumonia in China, 2019, NEJM, published online Jan 24 2020. Access here
  • Wu et al, Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020, Eurosurveillance, published online Jan 23 2020. Access here

Transmission

  • Rothe et al, Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany, NEJM, published online 30 Jan 2020. Access here
  • Li et al, Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia, NEJM, published online Jan 29 2020. Access here
  • Phan et al, Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam, NEJM, published online Jan 28 2020. Access here
  • Chan et al, A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster, The Lancet, published online Jan 24 2020. Access here

Disease modelling

  • Wu et al, Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study, The Lancet, published online 31 Jan 2020. Access here
  • Leung and Wu, Real-time nowcast and forecast on the extent of the Wuhan CoV outbreak, domestic and international spread, Media Conference Jan 27 2020. Download PDF
  • Imai et al, Report 3: Transmissibility of 2019-nCoV, published online Jan 25 2020. Download PDF
  • Chinazzi et al, Preliminary assessment of the international spreading risk associated with the 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan City, Center for Inference & Dynamics of Infectious Diseases, published online Jan 17 2020. Download PDF
  • Bogoch et al, Pneumonia of unknown etiology in Wuhan, China: Potential for international spread via commercial air travel, Journal of Travel Medicine, published online Jan 14 2020. Access here

Virology and diagnostics

  • Walls et al, Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein, Cell, published online 9 March 2020. Access here.
  • Wu et al, Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China, Cell Host & Microbe, published 7 Feb 2020. Access here.
  • Corman et al, Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR, Eurosurveillance, published online Jan 23 2020. Access here
  • Zhou et al, Discovery of a novel coronavirus associated with the recent pneumonia outbreak in 2 humans and its potential bat origin, bioRxiv, posted online Jan 23 2020. Access here
  • Killerby et al, Human coronavirus circulation in the United States 2014–2017, Journal of Clinical Virology, 101: 52–56, 2018. Access here

Publisher platforms with free papers relevant to the outbreak

Links

Global links

Australian links