November 22, 2017
During infectious disease outbreaks, clinical trials to test treatments face a number of challenges including:
- uncertainty about populations, interventions, comparators, effect size
- uncertainty about differences in treatment effect
- lead time, especially in fast moving outbreaks.
APPRISE researcher, Professor Steve Webb, presented a webinar discussing adaptive trial design and how trials can deal with uncertainty and be ready to use (but modifiable) prior to an epidemic or pandemic.
The webinar was hosted by Global Research Collaboration for Infectious Disease Preparedness (GloPID-R), an alliance to promote an effective research response within 48 hours of a significant infectious disease outbreak.