November 6, 2017
Managing uncertainty in clinical trials: the role of adaptive trial designs – a webinar + Q&A at 12:30 – 13:30 GMT
Uncertainty about populations, interventions, comparators, effect size, and heterogeneity of treatment effect, applies to all clinical trials, but it particularly affects trials that test the effectiveness of interventions during epidemics.
Another major challenge to conducting clinical trials during fast-moving epidemics is the lead-time needed to commence them. This presentation will discuss adaptive trial design as well as how such trials can deal with uncertainty and be implement-ready (but modifiable) prior to an epidemic.
The speaker is Professor Steve Webb who is a Senior Staff Specialist in Intensive Care Medicine at Royal Perth Hospital. Among his many roles, he is co-chair of the Australian government’s Clinical Trials Collaborative Forum and a Chief Investigator of the Australian Partnership for Preparedness Research on InfectiouS disease Emergencies (APPRISE).
The webinar is hosted by GloPID-R, the Global Research Collaboration for Infectious Disease Preparedness.